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    Seizures really are a side effect with Contrave and really should not be taken in individuals with seizure disorders. The drug may also raise blood pressure and pulse rate, and must not be used in people with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise blood pressure level and pulse rate and must stop used in patients with uncontrolled high blood pressure, along with by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients having a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert physicians and patients to the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation.

    The most common side effects reported with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.