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    These clinical trails will contain 53,000 patients for testing of the safety of an controversial class of inhaled asthma medications through which already are available for purchase. These medications are called long-acting beta-agonists (LABAs) when used in combination with inhaled steroids, a different class of asthma drugs, this in accordance with the FDA since Friday.

    According for the February 9, 2009, issue of Archives of Internal Medicine, researchers at Wake Forest University Baptist Medical Center checked out 18 randomized controlled trials that included close to 17,000 users. They figured people taking corticosteroids alone or in in conjunction with bronchodilators increased their likelihood of developing pneumonia by 60 to 70 percent. However, the increase in pneumonia was not associated with an increased probability of dying.

    A report on an internet medication discussion website revealed literally dozens of complaints by Advair users who experienced repeated bouts of pneumonia along with other low-grade infections, and various other side effects. In spite of patients' complaints and protests, their doctors insisted for the continued use of this drug.

    Asthma strikes when the airways get irritated forcing the muscles down the walls to tighten. The airway lining become inflamed creating a narrow passage, as inflammation takes hold. Patients being affected by asthma therefore find it hard to breathe. Several years of research finally ended in a method referred to as bronchial thermoplasty.